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Zepbound® vs. Wegovy®: Which Weight Loss Medication Is Right for You?

At Richmond Aesthetic Weight Loss, one of the most common questions we hear is: “Should I take Zepbound® or Wegovy®?” It’s a great question — because while both medications can be highly effective, they aren’t exactly the same.

If you’ve been struggling with weight loss despite your best efforts, you’re not alone. GLP-1 medications like Zepbound® (tirzepatide) and Wegovy® (semaglutide) have opened new doors for people seeking sustainable results. But which one is right for you? That depends on your goals, your health, and how your body responds.

Let’s look at what makes each option unique — and how we help you decide at Richmond Aesthetic Weight Loss.

Zepbound®: The Dual-Hormone Advantage

Zepbound® is an injectable medication containing tirzepatide, which mimics two hormones involved in appetite regulation — GLP-1 and GIP. That dual action may enhance the feeling of fullness and help control food cravings. In clinical studies, Zepbound users lost an average of up to 20% of their body weight. It’s a powerful option for those with a BMI of 30 or more, or 27+ with weight-related health conditions like high blood pressure or type 2 diabetes.

At our Richmond-based clinic, Zepbound costs $650 per month, and we accept most major insurance plans, including Anthem/BCBS and TRICARE. For those without coverage, we offer compounded GLP-1 options through a nationally accredited Virginia pharmacy.

Wegovy®: Trusted, Proven, and Effective

Wegovy® has helped people manage their weight through its active ingredient, semaglutide — a GLP-1 receptor agonist that helps you feel full sooner and stay full longer. Patients using Wegovy lost around 15% of their body weight in clinical trials. Like Zepbound, it’s a once-weekly injection for adults with a BMI of 30 or higher, or 27+ with related health concerns.

At Richmond Aesthetic Weight Loss, Wegovy is $500/month, and we work with insurance to help make treatment affordable.

What About Side Effects?

Both Zepbound and Wegovy can cause mild side effects, especially early on. Common symptoms include nausea, diarrhea or constipation, abdominal discomfort, and fatigue. Most ease over time. We’ll discuss these in your consultation and monitor your progress closely to keep you on track.

How Do You Know Which One Is Right for You?

That’s where we come in. During your consultation, Dr. Neil Zemmel and Sarah Ashcraft, PA-C will review your health history, goals, and preferences to help you choose between Zepbound, Wegovy, or a compounded alternative. Some patients start with one medication and switch based on how their body responds. We provide ongoing support and follow-ups to ensure your treatment works for the long haul.

Ready to Take the Next Step?

If you’re interested in starting a medically supervised weight loss plan in the greater Richmond area, we’d love to help. Whether you’re leaning toward Zepbound®, Wegovy®, or exploring other options, our experienced team is here to guide you. Contact us today to schedule your consultation.